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https://www.um.edu.mt/library/oar/handle/123456789/82224| Title: | Sickle Cell Amenia in association with α-thalassemia-2 : biosynthetic and hematological studies |
| Authors: | Felice, Alex Huisman, T. H. J. |
| Keywords: | Hemoglobin Hemoglobinopathy Sickle cell anemia |
| Issue Date: | 1978 |
| Publisher: | Directors of Sickle Cell Centers |
| Citation: | Felice, A., & Huisman, T. H. J. (1978). Sickle Cell Amenia in association with α-thalassemia-2 : biosynthetic and hematological studies, Puerto Rico. |
| Abstract: | Patients with Sickle Cell Anemia (SS) associated with homozygous α-thalassemia-2 (-α/-α; βs/βs) are difficult to detect because the in vitro synthesis of hemoglobin chains may be balanced after prolonged incubation (>120 min). However, a distinct imbalance can be present at early incubation times. We studied chain synthesis on whole cell globin at 10, 30, and 120 min incubation in 38 SS and 4 S/β°-thal patients and compared the data with hematological observations. |
| URI: | https://www.um.edu.mt/library/oar/handle/123456789/82224 |
| Appears in Collections: | Scholarly Works - FacM&SSur |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Sickle_Cell_Amenia_in_association_with_α-thalassemia-2_biosynthetic_and_hematological_studies_1978.pdf | 987.05 kB | Adobe PDF | View/Open |
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