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https://www.um.edu.mt/library/oar/handle/123456789/8223Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Mallia, Nicola | - |
| dc.contributor.author | Vassallo, Josanne | - |
| dc.date.accessioned | 2016-02-16T12:49:07Z | - |
| dc.date.available | 2016-02-16T12:49:07Z | - |
| dc.date.issued | 2015 | - |
| dc.identifier.citation | Malta Medical Journal. 2015, Vol. 27(4), p. 28-33 | en_GB |
| dc.identifier.uri | https://www.um.edu.mt/library/oar//handle/123456789/8223 | - |
| dc.description.abstract | This review aims to discuss the different genetic alterations that may come about and thus give rise to thyroid cancer. The importance of understanding the pathogenesis of this disease is in the use of these genetic alterations as prognostic markers and as targets in treatment. Principal alterations to these central pathways, namely the MAPK pathway and PI3K/AKT pathway, are mutations, increase in gene number, methylations and translocations. The effects of the environment on the progression of thyroid cancer, such as the effects of the microenvironment and exposure to endocrine disruptors, will also be discussed. | en_GB |
| dc.language.iso | en | en_GB |
| dc.publisher | Malta Medical Journal | en_GB |
| dc.rights | info:eu-repo/semantics/openAccess | en_GB |
| dc.subject | Thyroid gland -- Cancer | en_GB |
| dc.subject | Endocrine gland neoplasms | en_GB |
| dc.subject | Thyroid neoplasms | en_GB |
| dc.title | Pathogenesis of endocrine thyroid cancer | en_GB |
| dc.type | article | en_GB |
| dc.rights.holder | The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder. | en_GB |
| dc.description.reviewed | peer-reviewed | en_GB |
| Appears in Collections: | MMJ, Volume 27, Issue 4 MMJ, Volume 27, Issue 4 Scholarly Works - FacM&SMed | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Pathogenesis of endocrine thyroid cancer.pdf | 390.42 kB | Adobe PDF | View/Open |
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