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Title: | Hb G-Philadelphia in asociation with Hb S and α-Thalassemia-2 |
Authors: | Felice, Alex Ozdonmez, R. Headlee, M. E. Huisman, Titus Hendrik Jan |
Keywords: | Hemoglobin Hemoglobinopathy Sickle cell anemia Molecular microbiology |
Issue Date: | 1981 |
Citation: | Felice, A., Ozdonmez, R., Headlee, M. E., & Huisman, T. H. J. (1981). Hb G-Philadelphia in asociation with Hb S and α-Thalassemia-2. Annual Meeting of the Comprehensive Sickle Cell Centers and Sickle Cell Screening and Education Elinics, Hilton Head. |
Abstract: | The proportion of some a chain variants in the peripheral blood of heterozygotes has been a most useful marker for the number and activity of the a chain genes of human hemoglobin. Among these, Hb G-Philadelphia(or α2 68Lys β2) has been found in association with a heterozygous or a homozygous α-thal-2, a β-thal trait (AGAβTH) or a Hb S heterozygosity (ASAG) and a Hb S homozygosity (SSG). Hb G-Philadelphia heterozygotes differ in the proporticn of Hb G, MCV and MCH values and Σα/non-α biosynthetic ratios. Two categories have been noted in our laboratories among adult heterozygotes. |
URI: | https://www.um.edu.mt/library/oar/handle/123456789/82293 |
Appears in Collections: | Scholarly Works - FacM&SSur |
Files in This Item:
File | Description | Size | Format | |
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Hb_G-Philadelphia_in_asociation_with_Hb_S_and_α-Thalassemia-2_1981.pdf | 1.52 MB | Adobe PDF | View/Open |
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