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https://www.um.edu.mt/library/oar/handle/123456789/82539| Title: | Deletions and duplications of α or ζ globin genes in children with sickle cell anemia |
| Authors: | Felice, Alex McKie, Virgil C. McKie, Kathleen Mood Huisman, Titus Hendrik Jan |
| Keywords: | Hemoglobin Hemoglobinopathy Thalassemia Sickle cell anemia Molecular microbiology |
| Issue Date: | 1984 |
| Publisher: | American Society of Hematology |
| Citation: | Felice, A., McKie, V. C., McKie, K., & Huisman, T. H. J. (1984). Deletions and duplications of α or ζ globin genes in children with sickle cell anemia. Twenty-sixth Annual Meeting of the American Society of Hematology, Miami Beach. |
| Abstract: | DNA samples from 345 Black children, aged 0-18 years with SS, SC and Sβ+Thal were tested with restriction endonucleases and α or ζ globin DNA probes. A -3.7 kb type of α-Thal-2 (or -α/) was found in 34% with -α/αα and 4% with -α/-α (gene frequency= 0.20). None had the -4.2 kb type of α-Thal-2. The incidence of a-Thal-2 was the same among SS, SC and Sβ+Thal patients. |
| URI: | https://www.um.edu.mt/library/oar/handle/123456789/82539 |
| Appears in Collections: | Scholarly Works - FacM&SSur |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Deletions_and_duplications_of_α_or_ζ_globin_genes_in_children_with_sickle_cell_anemia_1984.pdf | 1.65 MB | Adobe PDF | View/Open |
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