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https://www.um.edu.mt/library/oar/handle/123456789/86690
Title: | Serotonin in health and disease |
Authors: | De Deurwaerdère, Philippe Di Giovanni, Giuseppe |
Keywords: | Serotonin -- Metabolism Receptor, serotonin, 5-HT2C Serotonin uptake inhibitors Dopaminergic neurons Molecular pharmacology |
Issue Date: | 2020 |
Publisher: | MDPI |
Citation: | De Deurwaerdère, P., & Di Giovanni, G. (2020). Serotonin in health and disease [Editorial]. International Journal of Molecular Sciences, 21(10), 3500. |
Abstract: | The International Journal of Molecular Sciences Special Issue “Serotonin in health and diseases” covers several aspects of the multiple and still mysterious functions of serotonin (5-hydroxytryptamine; 5-HT). 5-HT is neurotransmitter acting in the central nervous system (CNS), blood factor, and neurohormone controlling the function of several peripheral organs. Beyond its widespread implication in physiology, the 5-HT system is involved in numerous diseases of the CNS (e.g., depression, anxiety, schizophrenia, obsessive-compulsive disorders, addiction, Parkinson’s disease) and peripheral organs (e.g., gastrointestinal disorders, cardiac arrhythmia, hypertension). The Special Issue includes 14 articles dealing with molecular and cellular effects of 5-HT in periphery and CNS, from functional aspects in lower animals to clinical practices. Beyond physiology, the Special Issue also covers the influence of 5-HT and its receptors in the mechanism of action of psychoactive molecules including antipsychotics, antidepressants, and drug of abuse. The recent progress made on the function and dysfunction of the 5-HT system will certainly increase the understanding of the widespread role of 5-HT ultimately leading to better apprehend its targeting in human diseases. |
URI: | https://www.um.edu.mt/library/oar/handle/123456789/86690 |
Appears in Collections: | Scholarly Works - FacM&SPB |
Files in This Item:
File | Description | Size | Format | |
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Serotonin_in_health_and_disease_2020.pdf | 210.48 kB | Adobe PDF | View/Open |
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