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Please use this identifier to cite or link to this item: https://www.um.edu.mt/library/oar/handle/123456789/87251
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dc.contributor.authorRiva, Nicoletta-
dc.contributor.authorHickey, Kieron-
dc.contributor.authorGatt, Peter-
dc.contributor.authorGrima, Charlie-
dc.contributor.authorZammit, Daniel-
dc.contributor.authorAgeno, Walter-
dc.contributor.authorKitchen, Steve-
dc.contributor.authorMakris, Michael-
dc.contributor.authorGatt, Alexander-
dc.date.accessioned2022-01-19T11:27:51Z-
dc.date.available2022-01-19T11:27:51Z-
dc.date.issued2021-
dc.identifier.citationRiva, N., Vella, K., Hickey, K., Gatt, P., Grima, C., Zammit, D., ... & Gatt, A. (2021). The effect of DOAC-Stop® on several oral and parenteral anticoagulants. International Journal of Laboratory Hematology, 43, e171–e175.en_GB
dc.identifier.urihttps://www.um.edu.mt/library/oar/handle/123456789/87251-
dc.description.abstractDOAC-Stop® is a hydrophobic binding agent, containing activated charcoal, which can absorb the direct oral anticoagulants (DOACs) from plasma samples in vitro.1 It neutralized the effect of apixaban, edoxaban, rivaroxaban and dabigatran on routine coagulation assays, such as activated partial thromboplastin time (aPTT) and prothrombin time (PT)/international normalized ratio (INR).1-3 It has been proposed that DOAC-Stop® not only can identify which samples with prolonged coagulation assay results actually contain the DOACs,1 but might also aid in estimating the DOAC concentration by calculating a “correction ratio” of aPTT before/after DOAC-Stop® treatment, if the reagents are adequately sensitive to the DOACs.4en_GB
dc.language.isoenen_GB
dc.publisherWiley Online Libraryen_GB
dc.rightsinfo:eu-repo/semantics/restrictedAccessen_GB
dc.subjectAnticoagulants (Medicine)en_GB
dc.subjectAnticoagulants (Medicine) -- Administrationen_GB
dc.titleThe effect of DOAC-Stop® on several oral and parenteral anticoagulantsen_GB
dc.typearticleen_GB
dc.rights.holderThe copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder.en_GB
dc.description.reviewedpeer-revieweden_GB
dc.identifier.doi10.1111/ijlh.134877-
dc.publication.titleInternational Journal of Laboratory Hematologyen_GB
dc.contributor.author2Vella, Kevin-
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Scholarly Works - FacM&SPat

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