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https://www.um.edu.mt/library/oar/handle/123456789/88825| Title: | Isolated second-phase diabetes insipidus post-transsphenoidal surgery |
| Authors: | Montebello, Annalisa Portelli, Darryl Gruppetta, Mark |
| Keywords: | Metabolism -- Disorders Nervous system -- Surgery -- Complications Pituitary neoplasms Hyponatremia |
| Issue Date: | 2020-06 |
| Publisher: | BMJ Publishing Group LTD |
| Citation: | Montebello, A., Portelli, D., & Gruppetta, M. (2020). Isolated second-phase diabetes insipidus post-transsphenoidal surgery. BMJ Case Reports, 13(6), E235499. |
| Abstract: | A 57-year-old woman presented with severe lethargy, dizziness and nausea 1 week after transsphenoidal resection of a growth hormone secreting pituitary adenoma. She was found to have severe hyponatremia of 115 mmol/L. Importantly, she was neurologically intact and clinically euvolaemic. Her fluid intake was restricted and her sodium levels increased to 131 mmol/L over 4 days. She made a full recovery. She was diagnosed with isolated second-phase diabetes insipidus, a state of symptomatic hypoosmolar hyponatremia that usually occurs 7–10 days after transsphenoidal surgery. The sodium levels improve with fluid restriction. |
| URI: | https://www.um.edu.mt/library/oar/handle/123456789/88825 |
| Appears in Collections: | Scholarly Works - FacM&SMed |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Isolated second-phase diabetes insipidus post-transsphenoidal surgery.pdf Restricted Access | 240.27 kB | Adobe PDF | View/Open Request a copy |
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