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dc.contributor.authorAgius, Adrian M.-
dc.contributor.authorWake, Mark-
dc.contributor.authorPahor, Ahmes L.-
dc.contributor.authorSmallman, A.-
dc.date.accessioned2022-03-09T14:59:05Z-
dc.date.available2022-03-09T14:59:05Z-
dc.date.issued1995-
dc.identifier.citationAgius, A. M., Wake, M., Pahor, A. L., & Smallman, A. (1995). The effects of in vitro cotitine on nasal ciliary beat frequency. Clinical Otolaryngology & Allied Sciences, 20(5), 465-469.en_GB
dc.identifier.urihttps://www.um.edu.mt/library/oar/handle/123456789/90983-
dc.description.abstractCotitine is one of the main metabolites of nicotine. It is stable and in vivo has a relatively long circulating half life. Nasal ciliated cells from non-smoking individuals were exposed in vitro to solutions of cotitine corresponding to serum levels in active and passive smokers. Ciliary beat frequency was measured by a computerized photometric technique. There was a significant drop in ciliary beat frequency compared with control ciliated cells in phosphate buffered saline. It is concluded that cotitine in active or passive smoking has a marked effect on ciliary function. It may be a factor leading to diminished mucociliary clearance and persistent middle ear effusion.en_GB
dc.language.isoenen_GB
dc.publisherInternational Rhinologic Societyen_GB
dc.rightsinfo:eu-repo/semantics/restrictedAccessen_GB
dc.subjectCotinineen_GB
dc.subjectCilia and ciliary motionen_GB
dc.subjectCiliary body -- Diseasesen_GB
dc.titleThe effects of in vitro cotinine on nasal ciliary beat frequencyen_GB
dc.typearticleen_GB
dc.rights.holderThe copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holderen_GB
dc.description.reviewedpeer-revieweden_GB
dc.identifier.doi10.1111/j.1365-2273.1995.tb00083.x-
dc.publication.titleClinical Otolaryngology & Allied Sciencesen_GB
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