Please use this identifier to cite or link to this item: https://www.um.edu.mt/library/oar/handle/123456789/92626
Title: How low can you get?
Authors: Brincat, Mark
Muscat Baron, Yves
Galea, Raymond P.
Keywords: Oral contraceptives
Oral contraceptives -- Research
Oral contraceptives -- Side effects
Oral contraceptives -- Physiological effect
Issue Date: 2003
Publisher: New York Academy of Sciences
Citation: Brincat, M., Muscat Baron, Y., & Galea. R. P. (2003). How low can you get?. Annals of the New York Academy of Sciences, 997,158-162
Abstract: Since the early 1960s the side effects or oral contraceptives have been known to be related to the high doses (50 μg) of ethinyl estradiol used. Research has focused on reducing the dose of both the estrogen and progestin components to reduce these side effects. While reducing the dose of both components, the contraceptive efficacy has to be maintained so as to retain a satisfactory Pearl index. These requirements appear to have been attained with 24-day regimen of a low-dose pill (15 μg of ethinyl estradiol and 60 μg of gestedone) as one part of an open-label noncomparative multicenter study. This paper reports our unit's results, which indicate that the low-dose pill promises to reduce contraceptive--related side effects, to encourage better compliance, and as corollary, to retain a satisfactory Pearl Index
URI: https://www.um.edu.mt/library/oar/handle/123456789/92626
Appears in Collections:Scholarly Works - FacM&SOG

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