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DC Field | Value | Language |
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dc.contributor.author | Attard, Ritienne | - |
dc.contributor.author | Dingli, Philip | - |
dc.contributor.author | Doggen, Carine J. M. | - |
dc.contributor.author | Cassar, Karen | - |
dc.contributor.author | Farrugia, Rosienne | - |
dc.contributor.author | Bezzina Wettinger, Stephanie | - |
dc.date.accessioned | 2022-04-01T11:11:40Z | - |
dc.date.available | 2022-04-01T11:11:40Z | - |
dc.date.issued | 2021 | - |
dc.identifier.citation | Attard, R., Dingli, P., Doggen, C. J., Cassar, K., Farrugia, R., & Bezzina Wettinger, S. (2021). The impact of frequency, pattern, intensity, and type of alcohol consumption, and its combined effect with smoking on inflammation, lipid profile, and the risk of myocardial infarction. Journal of Public Health, 29, 611-624. | en_GB |
dc.identifier.uri | https://www.um.edu.mt/library/oar/handle/123456789/92730 | - |
dc.description.abstract | Aim To determine the risk of myocardial infarction (MI) associated with pattern, frequency, and intensity of alcohol consumption, type of alcoholic beverage, and the combined effect of alcohol and smoking on risk of MI, inflammation, and lipid profile. | en_GB |
dc.description.abstract | Method A total of 423 cases with a first MI and 465 controls from the Maltese Acute Myocardial Infarction (MAMI) Study were analysed. Data was collected through an extensive interviewer-led questionnaire, along with measurements of various blood parameters. Medians and the Mann–Whitney test were used to assess effect of different drinking patterns, frequency, intensity, and smoking and drinking combinations on hs-CRP and lipid profile. Odds ratios, adjusted for the conventional risk factors of MI (AdjORs), were calculated as an estimate of the relative risk of MI. | en_GB |
dc.description.abstract | Results Regular alcohol consumption protected against MI [AdjOR 0.6 (95% CI 0.4–0.9)] while daily binge drinking increased risk [AdjOR 5.0 (95% CI 1.6–15.0)] relative to regular drinkers who did not binge drink. Whereas moderate weekly consumption of wine protected against MI, high weekly consumption of beer conveyed a deleterious effect. Alcohol consumption decreased risk of MI independent of smoking status. Frequent alcohol consumption was associated with higher HDL-, non-HDL-, total cholesterol and triglycerides, and lower hs-CRP. Total and HDL-cholesterol increased and BMI decreased with increasing quantity of weekly alcohol consumption relative to the non-regular drinkers. The effect of smoking on lipid profile and hsCRP was less pronounced in current drinkers than in those who were non-regular drinkers. | en_GB |
dc.description.abstract | Conclusion The protective effect of alcohol consumption was dependent on the pattern, frequency, type, and intensity of alcohol consumed. Alcohol modified the effects of smoking on the lipid profile. Regular drinking attenuated the effect of smoking on hsCRP and lipid profile. | en_GB |
dc.language.iso | en | en_GB |
dc.publisher | Springer | en_GB |
dc.rights | info:eu-repo/semantics/restrictedAccess | en_GB |
dc.subject | Drinking of alcoholic beverages | en_GB |
dc.subject | Drinking of alcoholic beverages -- Health aspects | en_GB |
dc.subject | Myocardial infarction | en_GB |
dc.subject | Myocardial infarction -- Diagnosis | en_GB |
dc.subject | Inflammation | en_GB |
dc.subject | Lipids -- Research | en_GB |
dc.title | The impact of frequency, pattern, intensity, and type of alcohol consumption, and its combined effect with smoking on inflammation, lipid profile, and the risk of myocardial infarction | en_GB |
dc.type | article | en_GB |
dc.rights.holder | The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder. | en_GB |
dc.description.reviewed | peer-reviewed | en_GB |
dc.identifier.doi | 10.1007/s10389-019-01172-3 | - |
dc.publication.title | Journal of Public Health | en_GB |
Appears in Collections: | Scholarly Works - FacHScABS |
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