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https://www.um.edu.mt/library/oar/handle/123456789/93076| Title: | P51 variation in the ex vivo response to LPS stimulation in healthy volunteers : identification of extremes of monocyte function |
| Authors: | Farrugia, Rosienne Garner, Stephen F. Gray, Elaine Watkins, Nicholas A. Goodall, Alison H. Ouwehand, Willem H. |
| Keywords: | Inflammation -- Case studies Monocytes -- Reseach Cardiovascular system Laboratory medicine |
| Issue Date: | 2006 |
| Publisher: | Wiley-Blackwell Publishing Ltd. |
| Citation: | Farrugia, R., Garner, S. F., Gray, E., Watkins, N. A., Goodall, A. H., & Ouwehand, W. H. (2006). P51 variation in the ex vivo response to LPS stimulation in healthy volunteers : identification of extremes of monocyte function. Transfusion Medicine, 16, 46. |
| Abstract: | Numerous epidemiological and clinical studies have established a firm link between infection, the inflammatory response and cardiovascular disease. Furthermore, it is known that individuals differ in their responses to immune stimuli such as Lipopolysaccharide (LPS) that stimulates monocytes through Toll-like receptor 4 (TLR4). In this study we set out to identify healthy individuals with extremes of monocyte response to LPS stimulation. Once identified these individuals will be studied further to identify genes responsible for the observed differences. |
| URI: | https://www.um.edu.mt/library/oar/handle/123456789/93076 |
| Appears in Collections: | Scholarly Works - FacHScABS |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| P51_Variation_in_the_Ex_Vivo_Response_to_LPS_Stimulation_in_Healthy_Volunteers(2006).pdf Restricted Access | 459.91 kB | Adobe PDF | View/Open Request a copy |
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