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Title: | Effect of the macrophage migration inhibitory factor genotype on risk of myocardial infarction is modulated by other risk factors |
Authors: | Attard, Ritienne Dingli, Philip Doggen, Carine J. M. Cassar, Karen Farrugia, Rosienne Bezzina Wettinger, Stephanie |
Keywords: | Macrophage migration-inhibitory factors Myocardial infarction -- Risk factors Genetic polymorphisms |
Issue Date: | 2019 |
Publisher: | Springer Nature Limited |
Citation: | Attard, R., Dingli, P., Doggen, C. J. M., Cassar, K., Farrugia, R., & Wettinger, S. B. (2018). Effect of the macrophage migration inhibitory factor genotype on risk of myocardial infarction is modulated by other risk factors. European Journal of Human Genetics, 26, 278-279. |
Abstract: | AIM: To investigate the effect of the macrophage migration
inhibitory factor (MIF) genotype on the risk of myocardial infarction (MI), alone and in combination with other risk
factor of MI. METHOD: A total of 423 cases with a first MI and 465 controls from the Maltese Acute Myocardial Infarction (MAMI) Study were analysed. Data was collected through an interviewer-led questionnaire and various biochemical measurements. The MIF G-173C, C656G, and C624T polymorphisms were genotyped in all participants. Odds ratios (AdjORs) adjusted for conventional risk factors of MI were calculated as an estimate of the relative risk of MI. [excerpt] |
URI: | https://www.um.edu.mt/library/oar/handle/123456789/93654 |
Appears in Collections: | Scholarly Works - FacHScABS |
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