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DC Field | Value | Language |
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dc.contributor.author | Toulopoulou, T. | - |
dc.contributor.author | Grech, Anton | - |
dc.contributor.author | Sharma, T. | - |
dc.contributor.author | Morris, R. G. | - |
dc.contributor.author | Rabe-Hesketh, S. | - |
dc.contributor.author | Yakeley, J. | - |
dc.contributor.author | Murray, R. M. | - |
dc.date.accessioned | 2022-04-20T05:36:40Z | - |
dc.date.available | 2022-04-20T05:36:40Z | - |
dc.date.issued | 2000 | - |
dc.identifier.citation | Toulopoulou, T., Grech, A., Sharma, T., Morris, R. G., Rabe-Hesketh, S., Yakeley, J., & Murray, R. M. (2000). Relationship of whole brain volume MRI measures to neuropsychological performance in schizophrenic and healthy subjects. Schizophrenia Research, 41(1), 122-123. | en_GB |
dc.identifier.uri | https://www.um.edu.mt/library/oar/handle/123456789/94058 | - |
dc.description.abstract | Objective: To explore the relationship between whole brain volume MRI measures and performance on neuropsychological tests of intelligence, memory and shifting mental sets. Methods: Sixteen schizophrenic patients and 16 unrelated healthy controls matched for age, sex, handedness and social class underwent a series of neuropsychological assessments and a brain magnetic resonance imaging (MRI) scan. Neuropsychological function was assessed by administering a battery of tests including tests of: (1) Intelligence, assessed by the Wechsler Adult Intelligence Scale-Revised (WAIS-R); (2) Memory, measured by Russell's (1975) version of the Wechsler Memory Scale (WMS); and (3) Shifting Mental Sets, tested using the Trails B. MRI data were acquired using a single 1.5 Tesla General Electric Signa System. Whole brain volumetric measurements were made on spoiled-gradient images employing MEASURE, a software package that uses stereological principles. Results: In the patient sample, no significant associations were found between performance on any neuropsychological measure and whole brain volume. In the control sample, a positive correlation emerged between full-scale IQ and whole brain volume (r=0.48, P=0.02). Conclusion: Normal structure/function relationships change in pathological states. | en_GB |
dc.language.iso | en | en_GB |
dc.publisher | Elsevier | en_GB |
dc.rights | info:eu-repo/semantics/restrictedAccess | en_GB |
dc.subject | Brain -- Physiology | en_GB |
dc.subject | Schizophrenics -- Case studies | en_GB |
dc.subject | Brain -- Magnetic resonance imaging | en_GB |
dc.subject | Neuropsychological tests | en_GB |
dc.subject | WAIS-R Digit Span subtest | en_GB |
dc.title | Relationship of whole brain volume MRI measures to neuropsychological performance in schizophrenic and healthy subjects | en_GB |
dc.type | article | en_GB |
dc.rights.holder | The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder. | en_GB |
dc.description.reviewed | peer-reviewed | en_GB |
dc.publication.title | Schizophrenia Research | en_GB |
Appears in Collections: | Scholarly Works - FacM&SPsy |
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Relationship_of_whole_brain_volume_MRI_measures_to_neuropsychological_performance_in_schizophrenic_and_healthy_subjects_2000.pdf | 191.67 kB | Adobe PDF | View/Open |
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