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https://www.um.edu.mt/library/oar/handle/123456789/96559
Title: | A randomized, controlled trial on the effect of anesthesia on chronic pain after total knee arthroplasty |
Authors: | Sciberras, Stephen C. Vella, Adrian P. Vella, Bernice Spiteri, Jessica Antoinette Mizzi, Christabel Borg Xuereb, Keith LaFerla, Godfrey Grech, Godfrey Sammut, Fiona |
Keywords: | Arthroplasty, replacement, knee Total knee replacement Knee -- Surgery Chronic pain -- Treatment Postoperative pain -- Treatment Anesthesia -- Case studies |
Issue Date: | 2022 |
Publisher: | Future Medicine |
Citation: | Sciberras, S. C., Vella, A. P., Vella, B., Spiteri, J., Mizzi, C., Borg-Xuereb, K.,...Sammut, F. (2022). A randomized, controlled trial on the effect of anesthesia on chronic pain after total knee arthroplasty. Pain Management, 10.2217/pmt-2021-0081. |
Abstract: | The study sought to evaluate the influence of anesthesia on chronic pain after total knee arthroplasty (TKA). Methods: This was a single-center, randomized controlled study, with patients receiving a spinal anesthetic (SP) alone or a general anesthetic (GA) with femoral block, with follow-up at 3 and at 6 months. The primary outcome was the WOMACR score at 6 months. Results: 199 patients were enrolled. Group SP had better function (WOMAC: GA: 16.9 vs SP: 14.4, p = 0.015) and less pain (WOMAC pain: GA: 3.04 vs SP: 2.69, p = 0.02) at 3 months, but not at 6 months. Overall, 11% of patients had chronic postsurgical pain (CPSP), with Group GA having a higher incidence of CPSP at 6 months. Neuropathic pain increased during the follow-up and was more common in patients with CPSP. Conclusion: An SP reduces pain and incidence of CPSP after TKA. |
URI: | https://www.um.edu.mt/library/oar/handle/123456789/96559 |
Appears in Collections: | Scholarly Works - FacM&SSur Scholarly Works - FacSciSOR |
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File | Description | Size | Format | |
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A_randomized_controlled_trial_on_the_effect_of_anesthesia_on_chronic_pain_after_total_knee_arthroplasty_2022.pdf Restricted Access | 1.05 MB | Adobe PDF | View/Open Request a copy |
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