Please use this identifier to cite or link to this item: https://www.um.edu.mt/library/oar/handle/123456789/96559
Title: A randomized, controlled trial on the effect of anesthesia on chronic pain after total knee arthroplasty
Authors: Sciberras, Stephen C.
Vella, Adrian P.
Vella, Bernice
Spiteri, Jessica Antoinette
Mizzi, Christabel
Borg Xuereb, Keith
LaFerla, Godfrey
Grech, Godfrey
Sammut, Fiona
Keywords: Arthroplasty, replacement, knee
Total knee replacement
Knee -- Surgery
Chronic pain -- Treatment
Postoperative pain -- Treatment
Anesthesia -- Case studies
Issue Date: 2022
Publisher: Future Medicine
Citation: Sciberras, S. C., Vella, A. P., Vella, B., Spiteri, J., Mizzi, C., Borg-Xuereb, K.,...Sammut, F. (2022). A randomized, controlled trial on the effect of anesthesia on chronic pain after total knee arthroplasty. Pain Management, 10.2217/pmt-2021-0081.
Abstract: The study sought to evaluate the influence of anesthesia on chronic pain after total knee arthroplasty (TKA). Methods: This was a single-center, randomized controlled study, with patients receiving a spinal anesthetic (SP) alone or a general anesthetic (GA) with femoral block, with follow-up at 3 and at 6 months. The primary outcome was the WOMACR score at 6 months. Results: 199 patients were enrolled. Group SP had better function (WOMAC: GA: 16.9 vs SP: 14.4, p = 0.015) and less pain (WOMAC pain: GA: 3.04 vs SP: 2.69, p = 0.02) at 3 months, but not at 6 months. Overall, 11% of patients had chronic postsurgical pain (CPSP), with Group GA having a higher incidence of CPSP at 6 months. Neuropathic pain increased during the follow-up and was more common in patients with CPSP. Conclusion: An SP reduces pain and incidence of CPSP after TKA.
URI: https://www.um.edu.mt/library/oar/handle/123456789/96559
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Scholarly Works - FacSciSOR

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