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DC Field | Value | Language |
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dc.contributor.author | Yeaman, G. R. | - |
dc.contributor.author | Froebel, K. | - |
dc.contributor.author | Galea, G. | - |
dc.contributor.author | Ormerod, A. | - |
dc.contributor.author | Urbaniak, S. J. | - |
dc.date.accessioned | 2022-06-09T08:22:00Z | - |
dc.date.available | 2022-06-09T08:22:00Z | - |
dc.date.issued | 1991 | - |
dc.identifier.citation | Yeaman, G. R., Froebel, K., Galea, G., Ormerod, A., & Urbaniak, S. J. (1992). Discoid lupus erythematosus in an X‐linked cytochrome‐positive carrier of chronic granulomatous disease. British Journal of Dermatology, 126, 60-65. | en_GB |
dc.identifier.uri | https://www.um.edu.mt/library/oar/handle/123456789/97402 | - |
dc.description.abstract | A 13-year-old female presented with photosensitivity, recurrent aphthous ulcers and discoid lupus erythematosus (DLE)-like skin lesions. These symptoms have been linked to the carrier status of chronic granulomatous disease (CGD). Neutrophil (PMN) function was investigated by nitroblue tetrazolium reduction test and chemiluminescence. A severe impairment of PMN oxidative burst activity was revealed in spite of supranormal levels of cytochrome b245, Glucose-6-phosphate dehydrogenase activity was deficient. Her mother and two sisters also showed reduced PMN function. These findings are consistent with a cytochrome positive X-linked form of CGD with variable lyonization. DLE in association with the carrier status of this CGD variant has not been reported previously. | en_GB |
dc.language.iso | en | en_GB |
dc.publisher | Wiley-Blackwell Publishing Ltd. | en_GB |
dc.rights | info:eu-repo/semantics/restrictedAccess | en_GB |
dc.subject | Cytochromes | en_GB |
dc.subject | Lupus | en_GB |
dc.subject | Ulcers | en_GB |
dc.title | Discoid lupus erythematosus in an X-linked cytochrome-positive carrier of chronic granulomatous disease | en_GB |
dc.type | article | en_GB |
dc.rights.holder | The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder. | en_GB |
dc.description.reviewed | peer-reviewed | en_GB |
dc.publication.title | British Journal of Dermatology | en_GB |
Appears in Collections: | Scholarly Works - FacM&SPat |
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Discoid_lupus_erythematosus_in_an_Xlinked_cytochrome_positive_carrier_of_chronic_granulomatous_disease_1991.pdf Restricted Access | 2.83 MB | Adobe PDF | View/Open Request a copy |
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