Dr. DeMarco read for his undergraduate degree in Information Technology (majoring in Computer Science and Artificial Intelligence) from the University of Malta, which he followed with an M.Sc. in Computer Science and Artificial Intelligence from the same institution. Following this, he moved to the UK where he completed a Ph.D. at the Audio, Speech and Language Processing Laboratory of University of East Anglia, one of the major centers of speech processing. His area of research was in accent classification from speech using acoustic methods and machine learning.

Following his PhD, he joined the Institute of Space Sciences and Astronomy (ISSA) at the University of Malta as a post-doctoral researcher involved in the construction of various sub-elements of the Square Kilometre Array (SKA) radio telescope. Following this stint, he was promoted with a lectureship within the institute. As of January 2019, he has started a collaboration with the Institute of Linguistics and Language Technology, as an Affiliate member, focusing on speech technology research.