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Please use this identifier to cite or link to this item: https://www.um.edu.mt/library/oar/handle/123456789/104226
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dc.contributor.authorGrech, Godfrey-
dc.contributor.authorSaliba, Christian-
dc.contributor.authorBaldacchino, Shawn-
dc.contributor.authorAvellino, Roberto-
dc.contributor.authorValk, P. J. M.-
dc.contributor.authorDelwel, R.-
dc.date.accessioned2022-12-02T14:40:54Z-
dc.date.available2022-12-02T14:40:54Z-
dc.date.issued2012-
dc.identifier.citationGrech, G., Saliba, C., Baldacchino, S., Avellino, R., Valk, P. J. M., & Delwel, R. (2012). Transcript variants and isoforms of the phosphatase subunit PPP2CA and its regulatory binding partners in haematological malignancies. Virchows Archiv, 461(Suppl. 1), S166-S166.en_GB
dc.identifier.urihttps://www.um.edu.mt/library/oar/handle/123456789/104226-
dc.description.abstractObjective: The importance of feedback mechanisms involved in suppression of growth factor-induced signals is gaining importance both to understand molecular mechanisms of disease and also as potential therapeutic targets. Our previous studies show that erythroid differentiation can be blocked by constitutive expression of the pp2a inhibiting subunit, alpha4. The aim of this study was to identify variants and transcript isoforms of PPP2CA and the inhibiting subunits alpha4 and SET, using (1) cell lines derived from haematopoietic disease, and (2) Chronic Myeloid Leukemia (CML) and Acute Myeloid Leukemia (AML) patient material.en_GB
dc.language.isoenen_GB
dc.publisherSpringeren_GB
dc.rightsinfo:eu-repo/semantics/restrictedAccessen_GB
dc.subjectPhosphoprotein phosphatasesen_GB
dc.subjectCancer -- Molecular aspectsen_GB
dc.subjectHematological oncologyen_GB
dc.subjectProtein Isoformsen_GB
dc.titleTranscript variants and isoforms of the phosphatase subunit PPP2CA and its regulatory binding partners in haematological malignanciesen_GB
dc.title.alternativePS-10-019 Transcript variants and isoforms of the phosphatase subunit PPP2CA and its regulatory binding partners in haematological malignanciesen_GB
dc.typearticleen_GB
dc.rights.holderThe copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder.en_GB
dc.description.reviewedpeer-revieweden_GB
dc.publication.titleVirchows Archiven_GB
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