Please use this identifier to cite or link to this item:
https://www.um.edu.mt/library/oar/handle/123456789/107125
Title: | Complexity of Mycobacterium avium complex immune reconstitution inflammatory syndrome (MAC-IRIS) in a patient with HIV |
Authors: | Xerri, Thelma Borg, Janice Casha, Ramon Fsadni, Claudia |
Keywords: | Mycobacterium avium paratuberculosis -- Malta -- Case studies Mycobacterium avium paratuberculosis -- Treatment Immune reconstitution inflammatory syndrome HIV-positive persons AIDS (Disease) -- Patients |
Issue Date: | 2021 |
Publisher: | BMJ Group |
Citation: | Xerri, T., Borg, J., Casha, R., & Fsadni, C. (2021). Complexity of Mycobacterium avium complex immune reconstitution inflammatory syndrome (MAC-IRIS) in a patient with HIV. BMJ Case Reports, 14(9), e241813. |
Abstract: | We report a case of Mycobacterium avium complex immune reconstitution inflammatory syndrome (MAC-IRIS) in a patient with HIV positive. Initial presentation was that of a purpuric purple macular rash in-keeping with Kaposi sarcoma as an AIDS defining illness. Three weeks following the initiation of antiretroviral treatment (ART) she developed chest pain, dry cough and fever. A diagnosis of MAC was made through imaging and sputum cultures and appropriate treatment was initiated. Despite adequate management with evidence of good immunological and virological response, the patient represented with persistent symptoms. Repeat CT of the chest confirmed worsening lymphadenopathy with necrosis. Given these findings, a diagnosis of MAC-IRIS was made with resolution of fever after corticosteroids were initiated. This case highlights the importance of considering MAC as a cause of IRIS in severely immunosuppressed patients with HIV. |
URI: | https://www.um.edu.mt/library/oar/handle/123456789/107125 |
Appears in Collections: | Scholarly Works - FacM&SMed |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Complexity of Mycobacterium avium complex immune reconstitution inflammatory syndrome MAC IRIS in a patient with HIV 2021.pdf Restricted Access | 489.5 kB | Adobe PDF | View/Open Request a copy |
Items in OAR@UM are protected by copyright, with all rights reserved, unless otherwise indicated.