Fever : unmasked Brugada syndrome on ECG in adult patients with Covid-19

Abstract

Overview: Brugada syndrome is considered an autosomal dominant hereditary cardiovascular condition which usually is diagnosed frequently in male gender. The syndrome shows itself on ECG with particular and unique elevations which help immediately in the recognition. Treatment for the condition does not exist but precautions and surgical approach might be considered. Particular conditions can trigger, if genetic predisposition is present, such as febrile status and drugs leading to sudden death. Covid-19 is considered an infectious disease due to the virus Sars covid-19 found out in Wuhan to be a particular cluster of pneumonia. Symptoms associated with the following virus are dyspnea, febrile status, pneumonia and severe multiorgan failure in deteriorated patients. Treatments involved the management of the symptoms such as antibiotics, antipyretic and oxygen therapy when required. Method: The evidence dissertation explored the research question “In adult patients affected by Covid-19, does an ECG taken with fever versus an ECG with no fever help to unmask the Brugada syndrome?” of which the PICO elements are P: Adult patients affected by covid-19. I: ECG taken during fever, C: ECG taken with no fever, O: If the virus or the fever produced as a side effect will help in unmasking the Brugada Syndrome. Seven articles were retrieved from Google Scholar and included in the study supporting and providing information leading to the final answer such as the fever produced by the virus itself is responsible of the transient Brugada pattern. JBI tool was used along the study to appraise the articles underlining the weakness of the material used to due to the lack of studies and information related to the combination of the two conditions. Conclusion: more researches must be done in order to confirm the final result. While waiting for more results to confirm and give benefits to the hypothesis obtained from this study, education can be provided in order to increase awareness for health care providers and general public.