The link between diabetes and prostate cancer in adult men

Abstract

Background: Countless people worldwide have diabetes and prostate cancer, two widespread chronic ailments. Prostate cancer has become the second most common type of malignancy in males globally, while diabetes has been considered one of the ailments to watch out for through research. Although they are often regarded as distinct diseases, numerous research studies have hypothesized a possible association between them. This could mean that diabetes may lead to prostate cancer at any stage of diagnosis and treatment. At the same time, prostate cancer may also present the possibility of leading to diabetes among men. Research Question: According to the arguments presented in various studies, men with diabetes may be more susceptible to acquiring prostate cancer and developing severe forms of it too. Both conditions' complications can considerably affect clinical practice, resulting in poor patient outcomes. The research question is, “Does having diabetes increase the risk of prostate cancer among men?” PICO Elements: Population- Men, Intervention- Risk of prostate cancer, Comparison- Having diabetes increases the risk of prostate cancer, Outcome- If having diabetes increases prostate cancer in men Method and Criteria: This paper comprehensively analyzes the mentioned relationship by thoroughly reviewing previous research while proposing new possibilities and findings to effortlessly grant better insights into how one can diagnose practicing preventative measure concepts working efficiently and effectively to reduce potential threats. Two systematic reviews, two meta-analyses, and one cohort research were identified among the five critical papers and were critically reviewed using the appropriate CASP tools. Ethical concerns were taken into account. Peer-reviewed articles published in English from 2008 onwards were chosen as an inclusion criterion. The Outcome of the Search: The search suggests a negative correlation between diabetes mellitus and adenocarcinoma cancer risk. There may be an underlying mechanism whereby diabetes may decrease the risk of adenocarcinoma cancer. Prostate cancer screening and surveillance for diabetic men may be enhanced, and interventions to improve insulin resistance and lower inflammation may help lower the risk of prostate cancer in these men. Implications and Recommendations: For effective management of both conditions together, like blood sugar control alongside appropriate treatment for cancers, careful consideration should be given to their effect on each other's procedures leading up to possible harmful drug interactions or side effects that could frequently occur, causing difficulty controlling these illnesses thus lowering patients' quality of life. Although studies investigating the connection between diabetes and male prostate cancer have provided valuable insights, areas still require further research.