Please use this identifier to cite or link to this item:
https://www.um.edu.mt/library/oar/handle/123456789/88491
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Mifsud, Janet | - |
dc.contributor.author | Shabbi, H. | - |
dc.contributor.author | Soler, D. | - |
dc.date.accessioned | 2022-02-08T07:34:49Z | - |
dc.date.available | 2022-02-08T07:34:49Z | - |
dc.date.issued | 2006-09 | - |
dc.identifier.citation | Mifsud, J., Shabbi, H., & Soler, D. (2006). Modelling pharmacokinetics for antiepileptic drugs in paediatrics. European Journal of Neurology, 13(s2), 122-123. | en_GB |
dc.identifier.uri | https://www.um.edu.mt/library/oar/handle/123456789/88491 | - |
dc.description.abstract | AIMS: Most physicians use ad hoc reasoning in the design of dosage regimens for antiepileptic drugs in children as there is still a lack of satisfactory models and software packages that will allow accurate predictions of drug levels. | en_GB |
dc.description.abstract | METHODS: In this study, the value of a sparse data model, using AdaptĀ® software was developed for lamotrigine in paediatric patients. Plasma lamotrigine levels in 20 paediatric patients were measured. The pharmacokinetic parameters in the four groups(lamotrigine alone, valproate co-medication group, carbamazepine co-medication group, and clonazepam co-medication group) were estimated in this study using model independent pharmacokinetic equations. | en_GB |
dc.description.abstract | [excerpt] | en_GB |
dc.language.iso | en | en_GB |
dc.publisher | John Wiley & Sons, Inc. | en_GB |
dc.rights | info:eu-repo/semantics/restrictedAccess | en_GB |
dc.subject | Pharmacokinetics -- Mathematical models | en_GB |
dc.subject | Pharmacokinetics -- Data processing | en_GB |
dc.subject | Anticonvulsants -- Mechanism of action | en_GB |
dc.subject | Epilepsy in children | en_GB |
dc.title | Modelling pharmacokinetics for antiepileptic drugs in paediatrics | en_GB |
dc.type | article | en_GB |
dc.rights.holder | The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder. | en_GB |
dc.bibliographicCitation.conferencename | 10th Congress of the EFNS | en_GB |
dc.bibliographicCitation.conferenceplace | Glasgow, UK, 2006 | en_GB |
dc.description.reviewed | peer-reviewed | en_GB |
dc.publication.title | European Journal of Neurology | en_GB |
Appears in Collections: | Scholarly Works - FacM&SCPT |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Modelling pharmacokinetics for antiepileptic drugs in paediatrics.pdf Restricted Access | 51.84 kB | Adobe PDF | View/Open Request a copy |
Items in OAR@UM are protected by copyright, with all rights reserved, unless otherwise indicated.