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https://www.um.edu.mt/library/oar/handle/123456789/90983
Title: | The effects of in vitro cotinine on nasal ciliary beat frequency |
Authors: | Agius, Adrian M. Wake, Mark Pahor, Ahmes L. Smallman, A. |
Keywords: | Cotinine Cilia and ciliary motion Ciliary body -- Diseases |
Issue Date: | 1995 |
Publisher: | International Rhinologic Society |
Citation: | Agius, A. M., Wake, M., Pahor, A. L., & Smallman, A. (1995). The effects of in vitro cotitine on nasal ciliary beat frequency. Clinical Otolaryngology & Allied Sciences, 20(5), 465-469. |
Abstract: | Cotitine is one of the main metabolites of nicotine. It is stable and in vivo has a relatively long circulating half life. Nasal ciliated cells from non-smoking individuals were exposed in vitro to solutions of cotitine corresponding to serum levels in active and passive smokers. Ciliary beat frequency was measured by a computerized photometric technique. There was a significant drop in ciliary beat frequency compared with control ciliated cells in phosphate buffered saline. It is concluded that cotitine in active or passive smoking has a marked effect on ciliary function. It may be a factor leading to diminished mucociliary clearance and persistent middle ear effusion. |
URI: | https://www.um.edu.mt/library/oar/handle/123456789/90983 |
Appears in Collections: | Scholarly Works - FacM&SSur |
Files in This Item:
File | Description | Size | Format | |
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The_effects_of_in_vitro_cotinine_on_nasal_ciliary_beat_frequency.pdf Restricted Access | 447.03 kB | Adobe PDF | View/Open Request a copy |
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